Wound Healing, Tissue Structures, and Their Functions

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Primary wound healing can be observed in wounds with a slight loss of tissue having smooth edges. The edges of the injury are close to each other; the wound is clean, not contaminated with microbes or foreign bodies, and does not contain necrotic (dead) tissue (Kordestani, 2019). An example of such healing may be small postoperative scars, the edges tightly connected by suturing. They heal quickly with the formation of a minimal scar. Secondary wound healing is characteristic of injuries with extensive tissue damage, such as bitten ones (Kordestani, 2019). With severe burns and bedsores, this healing type also occurs since the wound must heal from the bottom to the edges, and it is impossible to perform surgical suturing. Tertiary healing presumes delayed closure of the injury, implying that the wound should be left open until it is free of germs (Kordestani, 2019). This type is observed in post-surgery cuts, especially in the abdominal or pelvic areas.

Reticular tissue is a type of connective tissue that forms the basis of hematopoietic organs (bone marrow, spleen, lymph nodes, and others.). It is part of the tonsils, dental pulp, the basis of the intestinal mucosa, and some other body parts. It consists of reticular cells; reticulin fibers are attached to the body and processes of cells, having a mesh arrangement and composed of thin reticulin fibrils, the basis of which is collagen. Their structure allows for providing support to the mentioned organs. Goblet cells can be found in all parts of the intestinal tract, but their maximum number is in the rectum, especially in the crypts of the colon. The major function of these cells is the production of mucins – high-molecular glycoproteins capable of forming a gel. Intestinal mucins form a surface layer of mucus, which facilitates the movement of the contents into the intestinal lumen and serves to protect its mucous membrane.

Reference

Kordestani, S. S. (2019). Atlas of wound healing: A tissue engineering approach. Elsevier Health Sciences.

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