Light Use in Cancer Treatment

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Chen, Juanjuan, et al. “Improved Photodynamic Anticancer Activity and Mechanisms of a Promising Zinc(II) Phthalocyanine-Quinoline Conjugate Photosensitizer In Vitro and In Vivo.” Biomedical Optics Express, vol. 11, no. 7, 2020, pp. 3900-3912.

While focusing on the use and effectiveness of light in cancer treatment, this article describes how researchers have been keen to identify and use photosensitizers (PSs) that are ideal and effective. This means that this article is directly related to the intended research study. The work is also significant and offers similar insights and arguments to the ones described in the other sources. The presented new information is that quinoline-8-yloxy-substituted zinc (II) phthalocyanine (ZnPc-Q1) could become a promising photosensitizer in the management and treatment of tumor cells (Chen et al. 3900).

The use of such photo-sensitizers can ensure that clinical outcomes are recorded in a timely manner. The notable strength of this article is that it goes further to identify ZnPc-Q1 as a possible candidate for using light therapy in the treatment of cancer. The outstanding aspect of this source is that ZnPc-Q1 is promising due to its chemical structure, absorption abilities, and reduced toxicity on the human skin.

dos Santos, Ancély, et al. “Photodynamic Therapy in Cancer Treatment – An Update Review.” Journal of Cancer Metastasis and Treatment, vol. 5, no. 1, 2019, pp. 25-34.

This article is relevant and informative since it explains how the use of light therapy could help more cancer patients to record positive health outcomes. The information available from this source is evidence-based, practical, and directly linked to what the other sources provide. The outstanding new information is that photodynamic therapy (PDT) is not known to disorient or compromise the other available treatment methods. Some of the strengths of this article are that the authors present a divergent view of the subject matter and examine how therapy could meet the demands of more patients (dos Santos et al. 28).

This piece of work also digs deeper to examine some of the unique benefits of light therapy and compares them with the other available options. There is no identifiable weakness in this article. The most interesting aspect of this article is that PDT is effective and capable of reducing the prolonged morbidity associated with the other treatment methods, such as radiotherapy and chemotherapy.

Gai, Shili, et al. “Recent Advances in Functional Nanomaterials for Light-Triggered Cancer Therapy.” NanoToday, vol. 19, no. 1, 2018, pp. 146-187.

In this work, the authors examine and describe some of the breakthroughs in the use of phototherapy in cancer treatment. The work relates to other sources directly because the available insights revolve around the use of light technology in cancer treatment. However, the authors have gone further to present additional information that is relevant and evidence-based. The reader understands that monotherapy and co-therapy could be used to improve safety and ensure that superior models are designed to make light therapy more efficient. The concept of co-therapies also emerges whereby professionals can use various nano-materials to support the delivery of desirable results (Gai et al. 147).

The major strength is that the article identifies different methods for supporting light therapy. The interesting aspect of such a source is that the authors have succeeded in outlining the unique challenges and strengths of each of the available therapeutic processes and how they can deliver desirable results in the area of cancer treatment.

Hu, Jing-Jing, et al. “Recent Advances in Photonanomedicines for Enhanced Cancer Photodynamic Therapy.” Progress in Materials Science, vol. 114, no. 1, 2020, pp. 1-14.

In this article, the reader realizes that the use of photodynamic therapy (PDT) can support the destruction of neo-plastic cells and lesions. This work resonates with the ideas and content intended for this discussion. The article offers concrete information that is related to the ideas described in the other sources. For instance, the authors describe how PDT is becoming relevant in the field of cancer management and treatment.

The identifiable strength is that the authors have succeeded in describing the unique issues, challenges, and opportunities surrounding the use of PDT (Hu et al. 3). The outstanding weakness is that the author has not outlined some of the best approaches to integrate PDT and ensure that it meets the demands of more patients suffering from different cancer. The emerging new information from this article is that there are some problems and gaps that are hampering the use and coordination of the unique elements needed for pursuing PDT. These include the insufficiency of photo-sensitizers (PSs), oxygen, and light.

Muniyandi, Kasipandi, et al. “Role of Photoactive Phytocompounds in Photodynamic Therapy of Cancer.” Molecules, vol. 25, no. 18, 2020, pp. 4102-4122.

The use of lighting technologies has become relevant in the field of cancer treatment. In this article, the authors identify photodynamic therapy (PDT) as a powerful approach for treating and eradicating various cancer types. Being a natural compound, light has little side-effects and helps anticancer properties. This article relates to the research topic since it describes how light could be used as a good candidate for dealing with cancerous cells.

This presented information in the topic directly relates to the content obtained from the other sources in this Annotated Bibliography. The different information that can help researchers focus on the best ways to treat cancer is the power of PDT (Muniyandi et al. 4102). This therapeutic approach is recent and capable of delivering meaningful results. The major strengths include the presentation of timely information, the description of the revolutionary approach, and the use of the latest research materials. The interesting aspect is the use of photoactive groups could deliver phototoxic effects and support the delivery of PDT outcomes in the management and treatment of specific cancers.

Shi, Huayun, and Peter J. Sadler. “How Promising is Phototherapy for Cancer.” British Journal of Cancer, vol. 123, no. 1, 2020, pp. 871-873.

In this article, the reader realizes that the presented ideas and arguments revolve around the selected research topic. The authors identify PDT, photothermal therapy (PTT), and the development of photoactivated chemotherapy (PACT) as some of the best approaches for oncological phototherapy. These insights are similar to the ideas and concepts received or presented in the other articles. The emerging new information from this source is that the researchers have presented PTT and PACT as additional therapy techniques for ensuring positive results in cancer treatment (Shi and Sadler 871).

The major strengths include that the concepts are applicable in different fields to treat and manage various cancers. The major weakness is that the work does not offer specific ways of using light therapeutic techniques to treat cancer. The interesting aspect of this source is that some of the achievements and developments recorded in the recent past can become the best approaches for guiding and informing future development in this field.

Starreveld, Daniëlle E. J., et al. “Light Therapy as a Treatment of Cancer-Related Fatigue in (non-)Hodgkin Lymphoma Survivors (SPARKLE Trial): Study Protocol of a Multicenter Randomized Controlled Trial.” BMC Cancer, vol. 18, no. 880, 2018, pp. 1-14.

In this paper, the authors examine the use of a new approach to treat fatigue related to cancer, also known as cancer-related fatigue (CRF). The authors indicated that this condition lacked an effective treatment plan. This work is relevant and relates to the research topic since it examines an issue to do with the use of light therapy to manage cancer fatigue. The work offers more or less the same arguments in comparison with the other sources. The emerging new information is that light therapy could become a powerful approach for dealing with fatigue associated with cancer (Starreveld et al. 3). The major strength is that the work is timely and informative. The outstanding weakness is that the selected article only focuses on a specific group or population, making the findings not conclusive or replicable globally. The interesting aspect of this source is that light therapy is effective in the treatment of fatigue and tiredness associated with different cancer types.

van Straten, Demian, et al. “Oncologic Photodynamic Therapy: Basic Principles, Current Clinical Status and Future Directions.” Cancers, vol.9, no. 2, 2017, pp. 19-72.

This article is relevant to the research topic because it describes photodynamic therapy (PDT) as one of the best methods for treating cancer. The emerging components are harmless but capable of damaging cancerous cells and inducing inflammatory immune responses. This work provides content that is similar to the information received from the other sources regarding the power of PDT in cancer treatment. The newly acquired information from this specific article is that many clinicians and hospitals are yet to fully embrace the power of PDT (van Straten et al. 20). The outstanding strength is that the work is timely and capable of meeting the demands of both medical professionals and cancer patients.

There is no identifiable weakness from the source. The interesting aspect is that the authors examine some of the gaps affecting the adoption of PDT therapy and propose the best ways to ensure that the method is available to more people suffering from different types of cancer. These ideas will support the completion of the intended research study and present additional insights for helping more cancer patients.

Wang, Kai, et al. “An Update in Clinical Utilization of Photodynamic Therapy for Lung Cancer.” Journal of Cancer, vol. 12, no. 4, 2021, pp. 1154-1160.

The authors of this article present powerful ideas that can help different researchers and professionals deal with lung cancer. The information is timely and revolves around the use of light in the treatment and management of cancer. The article is related to the other sources because it examines the use of PDT and its appropriateness in destroying various cancer cells (Wang et al. 1154). The new information gained from the source is that PDT could be applied to lung cancer to kill malignant cells. This approach will make it possible for practitioners and professionals to address the challenges patients encounter.

The weakness is that the work fails to offer additional insights for dealing with other cancer types and helping deliver timely results. The interesting aspect of the article is that the ideas could help future health professionals and researchers to identify some of the best ways to use PDT in the treatment of different cancer types and empower the affected patients to lead high-quality lives.

Yun, Seok Hyun, and Sheldon J. J. Kwok. “Light in Diagnosis, Therapy and Surgery.” Nature Biomedical Engineering, vol. 1, no. 1, 2017, pp. 1-8.

In this article, the authors describe how modern optical and light technologies are becoming relevant and applicable in the field of medicine. This work is relevant and resonates with the selected research topic. The work expands the materials and arguments presented in the other articles. Additionally, the emerging new information from this article is that the authors examine the unique fundamentals of natural light and some of the best approaches through which it could be applied in different health settings (Yun and Kwok 3). The identifiable weakness is that the authors fail to link the content directly to cancer treatment.

The strength is that the work describes the manner in which professionals could use such technologies in diagnosis and imaging. The consideration of these aspects can help more people improve the quality of medical care and treatment available to cancer patients. The interesting aspect is how professionals can embrace the use of light-based strategies and techniques to treat and manage cancer.

Works Cited

dos Santos, Ancély, et al. “Photodynamic Therapy in Cancer Treatment – An Update Review.” Journal of Cancer Metastasis and Treatment, vol. 5, no. 1, 2019, pp. 25-34.

Gai, Shili, et al. “Recent Advances in Functional Nanomaterials for Light-Triggered Cancer Therapy.” NanoToday, vol. 19, no. 1, 2018, pp. 146-187.

Hu, Jing-Jing, et al. “Recent Advances in Photonanomedicines for Enhanced Cancer Photodynamic Therapy.” Progress in Materials Science, vol. 114, no. 1, 2020, pp. 1-14.

Muniyandi, Kasipandi, et al. “Role of Photoactive Phytocompounds in Photodynamic Therapy of Cancer.” Molecules, vol. 25, no. 18, 2020, pp. 4102-4122.

Shi, Huayun, and Peter J. Sadler. “How Promising is Phototherapy for Cancer.” British Journal of Cancer, vol. 123, no. 1, 2020, pp. 871-873.

van Straten, Demian, et al. “Oncologic Photodynamic Therapy: Basic Principles, Current Clinical Status and Future Directions.” Cancers, vol.9, no. 2, 2017, pp. 19-72.

Wang, Kai, et al. “An Update in Clinical Utilization of Photodynamic Therapy for Lung Cancer.” Journal of Cancer, vol. 12, no. 4, 2021, pp. 1154-1160.

Yun, Seok Hyun, and Sheldon J. J. Kwok. “Light in Diagnosis, Therapy and Surgery.” Nature Biomedical Engineering, vol. 1, no. 1, 2017, pp. 1-8.

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Light Use in Cancer Treatment

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