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I need to find the appropriate articles which meet my inclusion criteria ( witho
I need to find the appropriate articles which meet my inclusion criteria ( without writing any thing as a paper) .. a list of the articles ( or collect them in one file)
Title: Clinical and Preclinical Evidence for RAAS Modulation in the Management of Chronic Pain Syndromes: A Systematic Review
Inclusion Criteria
1. Study Type:
Clinical trials, observational studies, and preclinical studies (animal models) that investigate the role of RAAS modulation in the management of chronic pain syndromes.
2. Interventions:
Studies examining RAAS modulators, such as ACE inhibitors, angiotensin receptor blockers (ARBs), direct renin inhibitors, and aldosterone antagonists.
3. Participants/Subjects:
– Clinical studies involving patients with chronic pain syndromes, such as fibromyalgia, neuropathic pain, or other chronic pain conditions.
– Preclinical studies involving animal models induced with chronic pain conditions.
4. Outcomes:
– Primary outcomes: Measures of pain intensity, frequency, and duration (e.g., Visual Analog Scale, Numerical Rating Scale, behavioral pain assessments in animal models).
– Secondary outcomes: Quality of life, functional improvement, biochemical markers of pain, side effects, and adverse events.
6. Publication Date:
Studies published within the last 20 years to ensure relevance and up-to-date evidence.
Exclusion Criteria
1. Study Type:
Case reports, editorials, opinion pieces, reviews, and meta-analyses.
2. Interventions:
Studies not focusing on RAAS modulation or involving interventions unrelated to the RAAS (e.g., other pharmacological treatments not targeting the RAAS).
3. Participants/Subjects:
– Clinical studies not involving patients with chronic pain syndromes.
– Preclinical studies not involving animal models of chronic pain.
4. Outcomes:
Studies not reporting pain-related outcomes or where pain outcomes are secondary and not adequately reported.
6. Publication Date:
Studies published more than 20 years ago, unless they are seminal works providing foundational knowledge.
7. Quality:
Studies with poor methodological quality or lacking sufficient detail to assess the impact of RAAS modulation on chronic pain outcomes.
Do you need this or any other assignment done for you from scratch?
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