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Introduction
Evidence-based practice is vital in the analysis of intervention results. It is essential to understand the principles of EBP in order to construct relevant research. According to Barretti (2015), a meta-analysis study is effective in providing the necessary information. The weak point of this article for the research is that the subject of treating dialysis-related peritonitis has little relevance. However, this paper provides a valuable example of conducting such research in treating dialysis complications, which is the relevant setting.
Main body
As Herrington et al. (2014) claim, it is crucial to conduct evidence-based risk evaluation for dialysis patients to carry out preventive treatment. Health-related quality of life (HRQoL) of dialysis patients has been the subject of specific scientific interest during the recent years. Researches also study other renal‐specific therapies that aim at the treatment and prevention of dialysis complications, such as stroke and other cardiovascular diseases. Modern researchers pay their attention to patient-oriented symptom assessment methods. According to Kestenbaum & Seliger (2017), such aspects of CKD treatment as proper timing of dialysis initiation are vital for patients’ well-being. The researchers have conducted the study of the influence of such timing, the positive aspect of which was patient-orientation. However, the results of the research did not show significant changes.
The research of depression and anxiety that dialysis patients experience takes a significant place among HRQoL studies. Dong et al. (2016) have conducted a research which highlighted that “Even mild depression is closely associated with global and specific cognitive impairment” (p. 118). However, the study indicates the lack of research behind the connection of depression and cognitive impairment, which is a significant limitation to the conclusive statement. Kimmel & Cukor (2019) provide the analysis of behavioral symptoms of depression among patients treated with dialysis, focusing on those that are often overlooked, such as noncompliance and conflicts with staff. Despite the focus on a rather narrow sample, the study draws essential connections between depression, anxiety, and quality of life of CKD patients.
Conclusion
While two previous studies focus on prevention and symptom assessment, the evidence-based research proposed by Palmer et al. (2016) is a case study on treatment results of 170 patients through antidepressants versus psychological training or placebo. The results showed no significant statistical difference and no positive effect of antidepressant treatment on the quality of life. The research focuses on all PICOT aspects. However, the study results are found to be inconclusive and demand further investigation.
References
- Barretti, P. (2015). Evidence-based medicine: An update on treatments for peritoneal dialysis-related peritonitis. World Journal of Nephrology, 4(2), 287-284. doi: 10.5527/wjn.v4.i2.287
- Dong, J., Pi, H.-C., Xiong, Z.-Y., Liao, J.-L., Hao, L., Liu, G.-L., … Zheng, Z.-X. (2016). Depression and cognitive impairment in peritoneal dialysis: A multicenter cross-sectional study. American Journal of Kidney Diseases, 67(1), 111–118. doi: 10.1053/j.ajkd.2015.06.025
- Herrington, W., Haynes, R., Staplin, N., Emberson, J., Baigent, C., & Landray, M. (2014). Evidence for the prevention and treatment of stroke in dialysis patients. Seminars in Dialysis, 28(1), 35–47. doi: 10.1111/sdi.12281
- Kestenbaum, B., & Seliger, S. L. (2017). Commentary on symptom management of the patient with CKD: The Role of Dialysis. Clinical Journal of the American Society of Nephrology, 12(4), 694–695. doi: 10.2215/cjn.11781116
- Kimmel, P. L., & Cukor, D. (2019). Anxiety symptoms in patients treated with hemodialysis: Measurement and meaning. American Journal of Kidney Diseases, 74(2), 145–147. doi: 10.1053/j.ajkd.2019.04.012
- Palmer, S. C., Natale, P., Ruospo, M., Saglimbene, V. M., Rabindranath, K. S., Craig, J. C., & Strippoli, G. F. (2016). Antidepressants for treating depression in adults with end-stage kidney disease treated with dialysis. Cochrane Database of Systematic Reviews. 23 (5), 1-48. doi: 10.1002/14651858.cd004541.pub3
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