COLLEAQUE POST 1OBSERVATIONAL STUDY DESIGNS Study 1: “Socio-economic Inequalitie

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COLLEAQUE POST 1OBSERVATIONAL STUDY DESIGNS
Study 1: “Socio-economic Inequalitie

COLLEAQUE POST 1OBSERVATIONAL STUDY DESIGNS
Study 1: “Socio-economic Inequalities on Cancer Mortality in Nine European Areas: The Effect of the Last Economic Recession”
The first study employs a cross-national ecological design to examine socio-economic inequalities in cancer mortality across nine European areas, with a specific focus on the impact of the last economic recession. Using mortality registries and census data, the researchers analyze broad trends and patterns at the population level. A strength of this approach lies in its multi-country perspective, providing a comprehensive understanding of regional disparities. However, the ecological design’s limitation is evident in its potential for ecological fallacy, as it aggregates data at the population level, overlooking individual nuances. While suitable for generating hypotheses, the design may benefit from complementing studies using individual-level data for more nuanced insights.
Study 2: “Antibiotic Use and the Development of Inflammatory Bowel Disease: A National Case-Control Study in Sweden”
The second study adopts a case-control design to investigate the relationship between antibiotic use and the development of inflammatory bowel disease (IBD) in Sweden. Drawing on national databases, medical records, and prescriiption records, the research efficiently explores potential risk factors for IBD. A notable strength of the case-control design is its effectiveness in studying rare outcomes, such as the development of IBD. However, the reliance on retrospective data introduces the possibility of recall bias in self-reported antibiotic use. The study’s focus on a national level enhances generalizability, but careful consideration of potential confounding factors is crucial for accurate interpretation.
Insights and Conclusions:
In the first study, the cross-national ecological design provides valuable insights into broad socio-economic patterns, but limitations in capturing individual-level associations should be acknowledged. While appropriate for generating hypotheses and understanding regional trends, researchers may need to consider more targeted study designs for in-depth exploration. In the second study, the case-control design efficiently addresses the research question regarding antibiotic use and IBD development, but the potential for recall bias underscores the need for cautious interpretation. Overall, both studies make appropriate design choices for their respective research questions, but researchers and readers should be mindful of the inherent limitations and potential biases associated with each approach.
References
Palència, L., Ferrando J., Marí-Dell’Olmo, M., Gotsens, M., Morrison, J., Dzurova, D., Lustigova, M., Costa, C., Rodríguez-Sanz, M., Bosakova, L, Santana, P., & Borrell, C. (2020). Socio-economic inequalities on cancer mortality in nine European areas: The effect of the last economic recessionLinks to an external site. Links to an external site.. Cancer Epidemiology, 69, Article 101827. https://doi.org/10.1016/j.canep.2020.101827
Nguyen, L. H., Örtqvist, A. K., Cao, Y., Simon, T. G., Roelstraete, B., Song, M., Joshi, A. D., Staller, K., Chan, A. T., Khalili, H., Olén, O., & Ludvigsson, J. F. (2020). Antibiotic use and the development of inflammatory bowel disease: A national case-control study in SwedenLinks to an external site. Links to an external site.. The Lancet. Gastroenterology & Hepatology, (11), 986–995. https://www.ncbi.nlm.nih.gov/pmc/articles/P
BY DAY 5 OF WEEK 3
Post at least two substantive responses to peers in a different group who analyzed at least one different article in their initial post. Include information from the Learning Resources in your responses as appropriate. You may expand on each peer’s posting with additional insight and resources about study designs, ask a question to further the discussion, or offer polite disagreement or critique supported with evidence. You may also make a suggestion or comment that guides or facilitates the discussion. At least one of your response posts should address the applicability of observational studies for improving population health status.
NB
MUST BE IN APA
REFERENCES MUST BE LESS THAN 5 YEARS
MUST ANSWER THE RESPONSE CORRECTLY
MUST BE IN APA

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