1. What are the clinical features of esophageal cancer in its early stages and a

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1. What are the clinical features of esophageal cancer in its early stages and a

1. What are the clinical features of esophageal cancer in its early stages and advanced stages?
2. What investigations are commonly used for the diagnosis and staging of esophageal cancer, and what are the specific findings associated with a barium swallow?
3. Which imaging modalities are employed for identifying the location, content, and metastases of esophageal cancer, and what is an additional option if CT scan results are inconclusive?
4. What role does transesophageal endoscopic ultrasound play in esophageal cancer diagnosis, and what other procedure can enhance its sensitivity and specificity for identifying lymph node disease?
5. What treatment options exist for esophageal cancer in curative and palliative settings, and under what indications are they employed?
6. What are the cancer-associated complications of esophageal cancer, and what is the overall prognosis?1. What are esophageal hypermotility disorders, and what are the two main causes of these disorders?
2. What is the known etiology of esophageal hypermotility disorders, and what are the speculated causes for distal esophageal spasm and hypercontractile esophagus?
3. According to the Chicago Classification of Esophageal Motility Disorders, what are the major motility disorders and the subcategories under incomplete LES relaxation?
4. What are the minor motility disorders, and how do they differ from major motility disorders in terms of symptoms and resolution?
5. What are the clinical features associated with esophageal hypermotility disorders?
6. Which investigations are commonly used for diagnosing esophageal hypermotility disorders, and what are the typical findings in upper endoscopy and esophageal barium swallow?
7. What is the significance of high-resolution esophageal manometry (HRM) in diagnosing esophageal motility disorders, and what are the indications for performing HRM?

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