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Introduction
Nowadays, everyone is bound in real-life problems. Those days are passed away when a person had little worries with a simple lifestyle, but now things are changed and this world has become the racing ground. Hypertension is a gift of this fast-moving world, HTN or HPN or hypertension is also referred to as high blood pressure. Hypertension is a medical condition in which blood pressure is chronically elevated. Basically, hypertension can be categorized into two: Primary hypertension and secondary hypertension.
There are different causes of hypertension some are: Obesity, Sodium sensitivity, Role of rennin, Insulin resistance, Sleep apnea, Genetics, Age, and Liquorices. Ace inhibitions and angiotensin block ii repeaters are widely used for renal failure patients for the treatment of hypertension (MacDougall, 2008). Both these products are well tolerated with few side effects. ACE inhibitors are widely used for failure heart treatment. According to the American College of Cardiology (ACC)/American Heart Association (AHA) guidelines for the treatment of chronic heart failure, even patients with the stage (Field, 2008).
Side effects
ACE inhibitors may induce skin rashes, angioneurotic edema, diarrhea, cough, and dizziness. Ace inhibitors usually do not cause a lot of side effects but a few of their side effects include: Cough, swelling around lips, can cause faintness, dizziness, and low blood pressure. Ace inhibitors can cause some problems to your kidneys or potassium level (Heart Failure Medicine, 2002).
On the other hand, angiotensin receptor blockers can cause dizziness, headache, hyperkalemia, rash, diarrhea, dyspepsia, abnormal liver function, muscle cramp, myalgia, back pain, lower abdomen pain insomnia, decreased hemoglobin levels, renal impairment; it can also cause nasal congestion.
Frequency
24 patients were selected with uncontrolled hypertension despite taking ACE inhibitors. Patients were taking 16 mg of candesartan per day with a combination of Plasma plasminogen activator inhibitor (PAI-1) antigen (Ag), tissue plasminogen activator (t-PA) Ag, and high C-reactive protein (hsCRP) levels, were
Measured during low salt intake at baseline after 2 weeks of ARB therapy. Results showed reduced systolic (155±17 vs. 139±13, p<0.001), and diastolic (91±9 vs. 81±8, p<0.001) blood pressures (BP). No major changes were measured in PAI-1 Ag (66±51 vs. 68±52, p=0.9), t-PA Ag (12.6±5.3 vs. 13.3±4.7, p=0.3), TAFI % activity (119±30 vs. 118±32, p=0.9) and hsCRP (3.9±3.4 vs. 3.6±3.6, p=0.7) levels after the addition of an ARB(Yusuf S, 2000).
ACB inhibitors and astigmatism blockers are more effective in patients with CKD (KODI, 2003). ACB inhibitors and ARB can be used combinable for the treatment of lower blood pressure and Proteinuria. With the use of AT1 blockers, about 7% of patients reported prescription-related issues within a few days of hospital discharge.
If Doctors continue prescribing it, it would be easy to control hypertension in patients, with few side effects; little more research is needed to overcome the side effects of these two new hypertension drugs. Some doctors prescribe a combination of these two products which also include some adverse effects. However, they can be controlled in different ways (Kober, 1996). Nitric Oxide and other naval therapies are the best replacement for these two drugs. With the aid of these therapies, a patient can easily fight against hypertension. There are different states of hypertension seen in different patients (Shawl, 2002).
According to which a doctor can not suggest the same treatment for all patients, treatments and drugs/ medicines varies from patient to patient depending upon their conditions and symptoms. Symptoms of hypertension also vary from patient to patient, according to which doctors prescribed treatments and drugs for hypertension patients. As it has been stated earlier that two types of hypertension are usually found in patients primary hypertension and secondary hypertension.
Naval therapies affect a lot in both types of hypertension. Naval therapies are one of the best options for the treatment of hypertension, though these therapies are not very common in the future it can be stated that these therapies would be among one of the best treatments for hypertension. The use of lipid-lowering products is also one of the best options for treating hypertension. Inhaling nitric oxide also helps in reducing hypertension in patients.
Proper assessments and diagnoses play an important role in treating hypertension disease as well as with the aid of proper on-time treatment a patient can easily fight against hypertension disease (Farar, 1985).
Therapies are one of the best options for treating hypertension, nitric oxide, and naval therapies can help a lot in fighting against hypertension in most patients. However, it might be possible that in some cases these techniques would not work in a better way as a combination of Ace inhibitors and ARB works, in that case, some measures are required to be taken for controlling the adverse effects of these drugs.
Pulmonary hypertension always requires proper on-time diagnosis and proper medication else it can get worse. Naval therapies are helpful in treating pulmonary disease on time (Sprung, 2005). A combination of ACE and ARB works well these days but in some cases it gets fails then different treatments are offered to treat hypertension. Delaying and unprescribed treatments make situations/diseases worst most of the time. So, it’s always recommended to use only prescribed medications and treatments for treating any disease.
References
IAIN C. MacDougall, (2008), the role of ACE inhibitors and angiotensin II receptor blockers in the response to epoetin. Web.
Katherine M. Field,( 2008), Knowing When to Play the Ace: The Use and Underuse of ACE Inhibitors in Primary Practice. Web.
Yusuf S (2000), ACE-Inhibitor Myocardial Infarction Collaborative Group. Long-term ACE-inhibitor therapy in patients with heart failure or left ventricular dysfunction: a systematic overview of data from individual patients. 355:1575-81.
Heart Failure Medicine,(2002). Web.
K/DOQI Clinical Practice Guidelines on Hypertension and Antihypertensive Agents in Chronic Kidney Disease,(2003). Web.
Kober L, (1996). Angiotensin-converting enzyme inhibition after myocardial infarction: The Trandolapril Cardiac Evaluation Study. Am Heart J; 132:235-43.
Shaul PW, (2002) Regulation of endothelial nitric oxide synthase: Location, location, location. Annu Rev Physiol 64:749-774.
Farrar DJ, 1985. Right ventricular function in an operating room model of mechanical left ventricular assistance and its effects in patients with depressed left ventricular function. Circulation. 72.
Sprung J, (2005), Impact of pulmonary hypertension on the outcomes of no cardiac surgery: predictors of preoperative morbidity and mortality. J Am Coll Cardiol; 45:1691-1699.
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